Published work relying on immunoGlobe services (selection):

  • Wild et al. (2011) Science 333:228-33.
  • Günther et al. (2009) J. Mol. Med. 87:31-41.
  • Pagenstecher et al. (2009) Hum. Mol. Genetics 18: 911–918.
  • Fritsche et al. (2008) Nature Genetics 40: 892-896.
  • Agerer et al. (2003) J. Biol. Chem. 278,: 42524–42531.
  • Butt et al. (2003) J. Biol. Chem. 278,: 15601-15607.

"Das Serum erkennt das nicht- rekombinante Protein noch bei einer Verdünnung von 1/5000 und verursacht auf dem Film kaum Hintergrundbanden! Ich bin begeistert! Auch das Präimmunserum liefert (…) so gut wie keinen Hintergrund! Wir denken deshalb auch schon über eine Programmverlängerung nach (Parken vom Superkaninchen)."

A customer's quote

 

Our specialization:

Antibodies against phospho sites / point mutations / isoforms / any other modification


Features that typically have been associated with monoclonal antibodies only, now are also possible with polyclonal rabbit antibodies - due to sophisticated immunization, purification, and depletion schemes on multiple proteins or peptides.

 

  • antibodies specifically recognizing a neo-epitope (e.g. a cleavage site) - but not the parental protein
  • antibodies discriminating between different isoforms, splicing variants, or mutants that differ in as few as one single (1) amino acid or, in extreme cases, even a single atom (Phe>Tyr, Tyr>Phe).
  • antibodies discriminating between different states of neighboring double-phosphorylation sites